General Information

  • ID:  hor002560
  • Uniprot ID:  A0A7M7GM99
  • Protein name:  Neuropeptide like precursor 1
  • Gene name:  LOC100577694
  • Organism:  Apis mellifera (Honeybee)
  • Family:  NA
  • Source:  animal
  • Expression:  NA
  • Disease:  NA
  • Comments:  NA
  • Taxonomy:  Apis (genus), Apini (tribe), Apinae (subfamily), Apidae (family), Apoidea (superfamily), Aculeata (infraorder), Apocrita (suborder), Hymenoptera (order), Endopterygota (cohort), Neoptera (infraclass), Pterygota (subclass), Dicondylia, Insecta (class), Hexapoda (subphylum), Pancrustacea, Mandibulata, Arthropoda (phylum), Panarthropoda, Ecdysozoa, Protostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
  • GO MF:  NA
  • GO BP:  GO:0007218 neuropeptide signaling pathway
  • GO CC:  NA

Sequence Information

  • Sequence:  SIATLAKNDDLPISLHDRMAENEDDEE
  • Length:  27
  • Propeptide:  MVEMAYIRKLTRTLPVLRFGEPHWEDISDLVCEMGLTGNHLVTLLLYVAVVNEIRLPLVTCQDEDSTQCMPKTAFLALLRHPEVSSSLAAYSRAARVTQDTKSRNDMAHLRALTEEGDDTEICVPGRVYLQLLKDPVVRGDLSAILNGRTQKVPDLLGRLIDDTDQMDAREYPFEYQKRSIATLAKNDDLPISLHDRMAENEDDEEKRAVISSSDHSIIRDYLPPNGRSEEQALRDFSMEKRNVGTLARDFALPPGRRNIASLMRDYDQSRENRVPFPGKRNVASLARTYTLPQNAGKRNVGSVAREHGLPYGKRYVASLARTGDLPIRGQRSVSSLARTGDLPVREQRSVSSLAKNSAWPVSLKRGIFLPGSVILRALSRQGRSFDSADTNARNDLLDLQALGNLRQSQENDYESEEKVNDSLKADSNIRRSKREIAFSDEYPLPVMQNANMFDYEEMMEALGGQYPNAEKRFMGTGSAPEMQPEVDQFGYPETFQANKRHIGALARLGWLPSLRTARFSRSPRYLVDRENPADGSSPNYSSNSSTRSLRPNLNPRTRYIQALHGDCRHGFKRFLLLPATDNNYFHQKLPSSLRSKSL
  • Signal peptide:  NA
  • Modification:  NA
  • Glycosylation:  NA
  • Mutagenesis:  NA

Activity

  • Function:  NA
  • Mechanism:  NA
  • Cross BBB:  NA
  • Target:  NA
  • Target Unid:  NA
  • IC50: NA
  • EC50: NA
  • ED50: NA
  • kd: NA
  • Half life: NA

Structure

  • Disulfide bond:  NA
  • Structure ID:  AF-A0A7M7GM99-F1(AlphaFold_DB_ID)

  • Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)
    •    hor002560_AF2.pdbhor002560_ESM.pdb

Physical Information

Mass: 350620 Formula: C125H201N35O51S
Absent amino acids: CFGQVWY Common amino acids: D
pI: 3.77 Basic residues: 3
Polar residues: 5 Hydrophobic residues: 8
Hydrophobicity: -97.41 Boman Index: -8624
Half-Life: 1.9 hour Half-Life Yeast: >20 hour
Half-Life E.Coli: >10 hour Aliphatic Index 83.33
Instability Index: 3774.81 Extinction Coefficient cystines: 0
Absorbance 280nm: 0

Literature

  • PubMed ID:  19576913
  • Title:  Mass Spectrometric Profiling of (Neuro)-Peptides in the Worker Honeybee, Apis Mellifera